Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2871287 | 0.89 | LMNA (0.32) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL2860238 | 0.89 | NPC1 (0.32) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL2866626 | 0.88 | BCL2 (0.35) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL2861106 | 0.88 | BCL2 (0.38) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL2867605 | 0.88 | NPC1 (0.32) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL2866858 | 0.87 | NPC1 (0.30) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL2862090 | 0.86 | NPC1 (0.32) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL2870677 | 0.84 | NPC1 (0.32) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL2861109 | 0.84 | LMNA (0.33) | LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2862705 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964860-B1 | ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER | TOSOH CORP (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-7838611-B2 | Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer | TOSOH CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| US-7678866-B2 | Polyethylene composition and process for producing same | TOSOH CORPORATION (JP) | 2010-03-16 | — | — | US | disclosed |
| US-20090137755-A1 | ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER | TOSOH CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20040214953-A1 | Polyethylene composition and process for producing same | TOSOH CORPORATION | 2004-10-28 | — | — | US | disclosed |