Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | HPGD | P15428 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | DHODH | Q02127 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19219784 | 0.93 | KDM4E (0.75) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL15506192 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL28914302 | 0.82 | KDM4E (0.80) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL42477 | 0.81 | DHODH (0.81) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL29788461 | 0.81 | DHODH (0.81) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL28574876 | 0.81 | MEN1 (0.75) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL12273377 | 0.80 | DHODH (0.80) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL8614842 | 0.80 | DHODH (0.72) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL2283172 | 0.80 | KDM4E (0.68) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL28572974 | 0.80 | KDM4E (0.80) | KDM4EALDH1A1HPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920115-A | Quinoline-4-formamide skeleton derivative and application thereof | 四川大学 | 2021-06-08 | — | — | CN | disclosed |