Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | DHODH | Q02127 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2286108 | 0.88 | CYP3A4 (0.69) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL28567496 | 0.84 | CA9 (0.74) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL2285157 | 0.83 | POLB (0.60) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL2286089 | 0.83 | ALDH1A1 (0.62) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL2281123 | 0.83 | MEN1 (0.62) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL19219784 | 0.83 | KDM4E (0.75) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL28574876 | 0.81 | MEN1 (0.75) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL28575804 | 0.80 | KDM4E (0.74) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL28914302 | 0.80 | KDM4E (0.80) | KDM4EKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL28568150 | 0.80 | RUVBL1 (0.79) | KDM4EKMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207773-A1 | NOVEL PHENYL-QUINOLINE-CARBOXYLIC ACID PYRIDINE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | NEUROSEARCH A/S (DK) | 2011-08-25 | — | — | US | claimed |
| US-20110207773-A1 | NOVEL PHENYL-QUINOLINE-CARBOXYLIC ACID PYRIDINE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | NEUROSEARCH A/S (DK) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207773-A1 | NOVEL PHENYL-QUINOLINE-CARBOXYLIC ACID PYRIDINE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | CHRNA5, CHRNA10, CHRNA6 | KDM4E 2310/4885KMT2A 2052/4885ALDH1A1 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.