SCHEMBL42477

SCHEMBL42477

COc1ccc(-c2cc(C(=O)O)c3ccccc3n2)cc1OC

nearest known ligand 0.81

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 8/20 0.81
KMT2A Q03164 3/20 0.71
KDM4E B2RXH2 6/20 0.71
ALDH1A1 P00352 5/20 0.71
MAPT P10636 4/20 0.71
SMN1; SMN2 Q16637 3/20 0.71
HPGD P15428 3/20 0.71
NPSR1 Q6W5P4 2/20 0.71
NPC1 O15118 1/20 0.71
LMNA P02545 1/20 0.71
NFKB1 P19838 1/20 0.71
RAB9A P51151 1/20 0.71
NFKB2 Q00653 1/20 0.71
RELA Q04206 1/20 0.71
ATM Q13315 1/20 0.71
MEN1 O00255 2/20 0.69
ACACA Q13085 1/20 0.67
POLB P06746 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29788461 1.00 DHODH (0.81) DHODHKMT2AKDM4EALDH1A1MAPT
SCHEMBL12273377 0.91 DHODH (0.80) DHODHKMT2AKDM4EALDH1A1MAPT
SCHEMBL8240361 0.90 DHODH (0.70) DHODHKMT2AKDM4EALDH1A1MAPT
SCHEMBL9865641 0.90 DHODH (0.70) DHODHKMT2AKDM4EALDH1A1MAPT
SCHEMBL28576456 0.89 DHODH (0.69) DHODHKMT2AKDM4EALDH1A1MAPT
SCHEMBL13056561 0.88 DHODH (0.71) DHODHKMT2AKDM4EALDH1A1MAPT
SCHEMBL20118104 0.88 DHODH (0.67) DHODHKMT2AKDM4EALDH1A1MAPT
SCHEMBL29674931 0.87 RAB9A (0.70) DHODHKMT2AKDM4EALDH1A1MAPT
SCHEMBL4602056 0.87 RAB9A (0.70) DHODHKMT2AKDM4EALDH1A1MAPT
SCHEMBL9867633 0.87 DHODH (0.80) DHODHKMT2AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-26 US claimed
US-11079372-B2 Polymers and conjugates comprising the same VENTANA MEDICAL SYSTEMS, INC. (US) 2021-08-03 US claimed
EP-3201628-A2 POLYMERS AND CONJUGATES COMPRISING THE SAME Ventana Medical Systems, Inc. (US) 2017-08-09 EP claimed
US-20170205399-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. 2017-07-20 US claimed
WO-2016050913-A2 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2016-04-07 WO claimed
EP-2444806-A2 Haptens, hapten conjugates, compositions thereof and method for their preparation and use Ventana Medical Systems, Inc. (US) 2012-04-25 EP claimed
US-20100297725-A1 Haptens, hapten conjugates, compositions thereof and method for their preparation and use VENTANA MEDICAL SYSTEMS, INC. 2010-11-25 US claimed
US-20100184087-A1 Haptens, hapten conjugates, compositions thereof and method for their preparation and use VENTANA MEDICAL SYSTEMS, INC. 2010-07-22 US claimed
WO-2010020672-A1 NOVEL PHENYL-QUINOLINE-CARBOXYLIC ACID PYRIDINE DERIVATIVES USEFUL AS MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS NEUROSEARCH A/S (DK) 2010-02-25 WO claimed
EP-2078197-A2 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE Ventana Medical Systems, Inc. (US) 2009-07-15 EP claimed
US-20080268462-A1 Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits VENTANA MEDICAL SYSTEMS, INC. 2008-10-30 US claimed
WO-2008063378-A9 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE VENTANA MED SYST INC (US) 2008-07-31 WO claimed
WO-2008063378-A2 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE VENTANA MEDICAL SYSTEMS, INC. (US) 2008-05-29 WO claimed
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-26 US disclosed
US-12553886-B2 Polymers and conjugates comprising the same VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-17 US disclosed
US-20250066426-A1 PEPTIDE NUCLEIC ACID CONJUGATES VENTANA MED SYST INC (US) 2025-02-27 US disclosed
US-20070197509-A1 Compositions and methods for modulating gated ion channels PAINCEPTOR PHARMA CORPORATION (CA) 2007-08-23 US disclosed
US-20070197509-A1 Compositions and methods for modulating gated ion channels PAINCEPTOR PHARMA CORPORATION (CA) 2007-08-23 US disclosed
US-20070060573-A1 Acyltryptophanols BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-03-15 US disclosed
US-5071987-A Quinoline dyes; colorfastness BASF AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080268462-A1 Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits HRH4, CRBN, NCDN DHODH 1077/4885KMT2A 3827/4885KDM4E 3532/4885
US-12553886-B2 Polymers and conjugates comprising the same POLL, INCENP, POLI DHODH 358/4885KMT2A 1495/4885KDM4E 2159/4885
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME POLD1, POLL, INCENP DHODH 415/4885KMT2A 1085/4885KDM4E 1567/4885
US-20100297725-A1 Haptens, hapten conjugates, compositions thereof and method for their preparation and use CRBN, GABBR1, SHBG DHODH 1439/4885KMT2A 3542/4885KDM4E 3907/4885
US-20070060573-A1 Acyltryptophanols FSHR, NPY1R, NPY2R DHODH 3439/4885KMT2A 916/4885KDM4E 2399/4885
US-20070197509-A1 Compositions and methods for modulating gated ion channels KCNN3, KCNN2, HCN3 DHODH 3771/4885KMT2A 2807/4885KDM4E 2625/4885
US-20250066426-A1 PEPTIDE NUCLEIC ACID CONJUGATES PCNA, PARG, POLL DHODH 4561/4885KMT2A 1725/4885KDM4E 2697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.