SCHEMBL2857597

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2861737	0.86	MAP2K4 (0.43)	MAP2K4HTR7TTKAURKANTRK1
	SCHEMBL2863456	0.82	TTK (0.48)	MAP2K4HTR7TTKAURKANTRK1
	SCHEMBL2863072	0.75	TTK (0.47)	MAP2K4HTR7TTKNTRK1CLK2
	SCHEMBL14516332	0.74	AURKA (0.59)	MAP2K4HTR7TTKAURKANTRK1
	SCHEMBL2859865	0.73	MAP2K4 (0.51)	MAP2K4HTR7AURKANTRK1CLK2
	SCHEMBL4333049	0.73	GSK3B (0.56)	CLK2DYRK1AGSK3AGSK3BADORA2A
	SCHEMBL4149447	0.72	CLK2 (0.47)	MAP2K4HTR7AURKANTRK1CLK2
	SCHEMBL27536142	0.72	CHUK (0.46)	MAP2K4HTR7TTKNTRK1MAP4K4
	SCHEMBL2860721	0.71	AXL (0.61)	MAP2K4TTKAURKAFGFR1TAAR1
	SCHEMBL4152871	0.71	MAP2K4 (0.46)	MAP2K4HTR7TTKNTRK1CLK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.