SCHEMBL2859865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22446034	0.86	MAP2K4 (0.59)	MAP2K4AURKAAXLCLK2DYRK1A
	SCHEMBL2862716	0.82	NTRK1 (0.55)	MAP2K4AURKANTRK1HTR7
	SCHEMBL2857593	0.82	MAP2K4 (0.48)	MAP2K4AURKANTRK1HTR7TDO2
	SCHEMBL14516332	0.81	AURKA (0.59)	MAP2K4AURKANTRK1HTR7ADORA2A
	SCHEMBL2860721	0.81	AXL (0.61)	MAP2K4AURKAAXLMAP2K7MAPK1
	SCHEMBL2864682	0.80	MAPKAPK2 (0.50)	MAP2K4AURKAADORA2AMAPKAPK2
	SCHEMBL2868118	0.79	MAP2K4 (0.48)	MAP2K4NTRK1HTR7ADORA2ATDO2
	SCHEMBL2857674	0.78	MAP2K4 (0.60)	MAP2K4MAP2K7MAPK1MAPKAPK3MAPK6
	SCHEMBL2860957	0.76	AURKA (0.66)	MAP2K4AURKAHTR7ADORA2ATDO2
	SCHEMBL2862227	0.76	ADORA2A (0.49)	MAP2K4AURKAHTR7ADORA2ATDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.