SCHEMBL2863072

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2863456	0.86	TTK (0.48)	TTKNTRK1FYNLRRK2CLK2
	SCHEMBL2862698	0.82	NTRK1 (0.44)	TTKNTRK1FYNLRRK2CLK2
	SCHEMBL2864166	0.82	NTRK1 (0.49)	TTKNTRK1FYNLRRK2CLK2
	SCHEMBL2864633	0.81	MAP2K4 (0.47)	TTKNTRK1FYNLRRK2MAP2K4
	SCHEMBL2864790	0.80	CDK2 (0.49)	TTKLRRK2CLK2DYRK1ATUBB4A
	SCHEMBL2859116	0.78	MAP2K4 (0.48)	TTKNTRK1FYNLRRK2MAP2K4
	SCHEMBL4380129	0.77	NTRK1 (0.43)	TTKNTRK1FYNLRRK2CLK2
	SCHEMBL2862624	0.76	NTRK1 (0.55)	TTKNTRK1FYNCLK2CLK3
	SCHEMBL2857597	0.75	MAP2K4 (0.41)	TTKNTRK1FYNLRRK2CLK2
	SCHEMBL2861298	0.74	DYRK1A (0.49)	NTRK1LRRK2DYRK1AMAP2K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.