Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.31 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.31 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19117165 | 0.80 | KDM1A (0.35) | BRS3NPY5RKDM1ADAOYTHDF3 | |
| SCHEMBL19521677 | 0.72 | NPY5R (0.44) | BRS3NPY5RKDM1ADAO | |
| SCHEMBL22365025 | 0.68 | — | — | |
| SCHEMBL19077856 | 0.68 | KDM1A (0.35) | NPY5RKDM1AYTHDF3YTHDF1YTHDF2 | |
| SCHEMBL30077041 | 0.66 | NPY5R (0.43) | NPY5RKDM1A | |
| SCHEMBL15347477 | 0.66 | NPY5R (0.43) | NPY5RKDM1A | |
| SCHEMBL3712482 | 0.66 | — | — | |
| SCHEMBL19087053 | 0.65 | CCNA2 (0.32) | NPY5RKDM1A | |
| Hydrochloric Acid SCHEMBL4228688 | 0.64 | — | — | |
| SCHEMBL30364270 | 0.62 | GSK3B (0.41) | BRS3NPY5RKDM1AYTHDF3YTHDF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112135825-A | Plasma kallikrein inhibitors and uses thereof | 夏尔人类遗传性治疗公司 | 2020-12-25 | — | — | CN | disclosed |