Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 11/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28582168 | 0.84 | KMT2A (0.43) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28567907 | 0.83 | NPC1 (0.51) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14024175 | 0.81 | NPC1 (0.47) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28572762 | 0.81 | HPGD (0.44) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28216083 | 0.80 | RAB9A (0.46) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28914211 | 0.79 | KCNK3 (0.57) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7829720 | 0.79 | SMO (0.50) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28571714 | 0.77 | GPR27 (0.55) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28296314 | 0.75 | MAOB (0.44) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10602785 | 0.75 | RAB9A (0.51) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084110-B | 3-aminobenzo [ d ] isothiazole, derivative and synthetic method thereof | 湘潭大学 | 2021-05-07 | — | — | CN | disclosed |