SCHEMBL2857632

SCHEMBL2857632

Cc1cc(C)c2c(c1)C=CC2[Zr](Cl)(Cl)(=C(c1ccccc1)c1ccccc1)C1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2867840 0.89 LMNA (0.32) LMNAALDH1A1
SCHEMBL2871088 0.89 LMNA (0.33) LMNAALDH1A1
SCHEMBL2858502 0.87 MEN1 (0.31) LMNA
SCHEMBL2872271 0.86 LMNA (0.32) LMNA
SCHEMBL2871040 0.86 KCNK3 (0.31) LMNA
SCHEMBL2870066 0.85 LMNA (0.30) LMNA
SCHEMBL2861483 0.85 LMNA (0.31) LMNA
SCHEMBL2868038 0.85
SCHEMBL2870325 0.84 LMNA (0.33) LMNA
SCHEMBL2866135 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed