Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 2/20 | 0.75 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17005835 | 0.91 | VEGFA (0.60) | VEGFAEGLN1KDM4EKMT2AMEN1 | |
| SCHEMBL17005863 | 0.89 | VEGFA (0.58) | VEGFAEGLN1KDM4EKMT2AMEN1 | |
| SCHEMBL28566307 | 0.88 | VEGFA (0.82) | VEGFAEGLN1KMT2AMEN1FAAH | |
| SCHEMBL28570561 | 0.88 | VEGFA (0.79) | VEGFAEGLN1KMT2AMEN1TP53 | |
| SCHEMBL17005956 | 0.88 | VEGFA (0.56) | VEGFAEGLN1KDM4EKMT2AMEN1 | |
| SCHEMBL28579853 | 0.87 | VEGFA (0.74) | VEGFAEGLN1KDM4EKMT2AMEN1 | |
| SCHEMBL28576610 | 0.86 | VEGFA (0.65) | VEGFAEGLN1KDM4EKMT2AMEN1 | |
| SCHEMBL28572828 | 0.86 | VEGFA (0.70) | VEGFAEGLN1KDM4EKMT2AMEN1 | |
| SCHEMBL28914231 | 0.86 | VEGFA (0.76) | VEGFAEGLN1FAAHIDO1TDO2 | |
| SCHEMBL28572935 | 0.86 | VEGFA (0.76) | VEGFAEGLN1TP53MAPK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | disclosed |