Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Hydroxy Quinaldine SCHEMBL4950968 | 0.98 | METAP2 (0.77) | METAP2CYP1A2MAPTGAAPLAU | |
| 8-Hydroxy Quinaldine SCHEMBL6760796 | 0.98 | METAP2 (0.77) | METAP2CYP1A2MAPTGAAPLAU | |
| 8-Hydroxy Quinaldine SCHEMBL29483489 | 0.89 | METAP2 (1.00) | METAP2CYP1A2MAPTPLAUNCF1 | |
| 8-Hydroxy Quinaldine SCHEMBL297247 | 0.89 | METAP2 (1.00) | METAP2CYP1A2MAPTPLAUNCF1 | |
| 8-Hydroxy Quinaldine SCHEMBL9154369 | 0.87 | METAP2 (0.96) | METAP2CYP1A2MAPTPLAUNCF1 | |
| 8-Hydroxy Quinaldine SCHEMBL4762935 | 0.87 | METAP2 (0.96) | METAP2CYP1A2MAPTPLAUNCF1 | |
| 8-Hydroxy Quinaldine SCHEMBL4286984 | 0.87 | METAP2 (0.96) | METAP2CYP1A2MAPTPLAUNCF1 | |
| 8-Hydroxy Quinaldine SCHEMBL9154936 | 0.87 | METAP2 (0.96) | METAP2CYP1A2MAPTPLAUNCF1 | |
| 8-Hydroxy Quinaldine SCHEMBL22734876 | 0.87 | METAP2 (0.96) | METAP2CYP1A2MAPTPLAUNCF1 | |
| 8-Hydroxy Quinaldine SCHEMBL7179747 | 0.87 | METAP2 (0.96) | METAP2CYP1A2MAPTPLAUNCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112912372-A | Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element | 东曹株式会社 | 2021-06-04 | — | — | CN | disclosed |