Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854048 | 0.86 | MAPT (0.50) | CCR1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2852110 | 0.85 | SMN1; SMN2 (0.54) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL8631115 | 0.84 | KMT2A (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2856664 | 0.83 | CYP1A2 (0.55) | ALDH1A1RXFP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2859981 | 0.83 | KDM4E (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13513684 | 0.81 | CCR1 (0.54) | CCR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14539381 | 0.79 | CCR1 (0.42) | CCR1ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL2855798 | 0.77 | MAPT (0.45) | CCR1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2858063 | 0.76 | MAPT (0.57) | CCR1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8630975 | 0.76 | PTGS2 (0.59) | ALDH1A1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |