Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852110 | 0.86 | SMN1; SMN2 (0.54) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2859981 | 0.84 | KDM4E (0.50) | CYP1A2CYP2D6CYP2C19RAB9ANPC1 | |
| SCHEMBL2857713 | 0.83 | CCR1 (0.49) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2860020 | 0.80 | KDM4E (0.51) | RAB9ANPC1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL2859050 | 0.80 | PTGS1 (0.46) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL2859651 | 0.77 | MAPT (0.46) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2858063 | 0.77 | MAPT (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2858311 | 0.77 | RAB9A (0.47) | CYP3A4CYP2C19RAB9ANPC1ALDH1A1 | |
| SCHEMBL2854156 | 0.76 | ROCK2 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19RAB9A | |
| SCHEMBL2856049 | 0.76 | ATM (0.53) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |