Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995830 | 0.95 | HPGD (0.48) | RECQLHPGDEPHX1GPR119KDM4E | |
| SCHEMBL22680079 | 0.86 | GAA (0.43) | RECQLHPGDEPHX1GPR119MAPT | |
| SCHEMBL22680073 | 0.86 | GAA (0.43) | RECQLHPGDEPHX1GPR119MAPT | |
| SCHEMBL22680078 | 0.86 | GAA (0.43) | RECQLHPGDEPHX1GPR119MAPT | |
| SCHEMBL28577921 | 0.82 | HPGD (0.49) | RECQLHPGDEPHX1GPR119KDM4E | |
| SCHEMBL30659463 | 0.81 | HPGD (0.46) | RECQLHPGDEPHX1GPR119KDM4E | |
| SCHEMBL8329687 | 0.80 | GPR119 (0.45) | RECQLHPGDEPHX1GPR119GAA | |
| SCHEMBL18285469 | 0.79 | EPHX1 (0.52) | RECQLHPGDEPHX1GPR119KDM4E | |
| SCHEMBL2319139 | 0.79 | GAA (0.41) | MAPTTHRBGAAALDH1A1MEN1 | |
| SCHEMBL1189317 | 0.78 | ALDH1A1 (0.56) | RECQLHPGDKDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778299-B | Piperazine ureido derivatives, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-112778299-A | Piperazine ureido derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-05-11 | — | — | CN | disclosed |