Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3528493 | 0.83 | EPHX1 (0.78) | PKMHTTKCNMA1EPHX1LMNA | |
| SCHEMBL29886513 | 0.83 | EPHX1 (0.78) | PKMHTTKCNMA1EPHX1LMNA | |
| SCHEMBL16160857 | 0.81 | MAPT (0.56) | PKMHTTKCNMA1LMNAALDH1A1 | |
| Iodide SCHEMBL30758664 | 0.81 | EPHX1 (0.77) | PKMHTTKCNMA1EPHX1LMNA | |
| SCHEMBL16592675 | 0.81 | EPHX1 (0.72) | PKMHTTKCNMA1EPHX1LMNA | |
| SCHEMBL28916579 | 0.80 | MAPT (0.58) | KCNMA1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL29168827 | 0.80 | KCNMA1 (0.78) | PKMHTTKCNMA1EPHX1LMNA | |
| SCHEMBL28589695 | 0.79 | ALDH1A1 (0.69) | PKMHTTKCNMA1EPHX1LMNA | |
| SCHEMBL16592660 | 0.78 | HTT (0.66) | PKMHTTKCNMA1EPHX1ALDH1A1 | |
| SCHEMBL28577326 | 0.78 | KCNMA1 (0.71) | PKMHTTKCNMA1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061098-B | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113061098-A | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-07-02 | — | — | CN | disclosed |