Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.67 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.63 |
| ▸ | TYK2 | P29597 | 1/20 | 0.63 |
| ▸ | P2RX1 | P51575 | 12/20 | 0.62 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30216760 | 1.00 | TMPRSS4 (0.67) | TMPRSS4KCNMA1JAK2TYK2P2RX1 | |
| SCHEMBL538439 | 0.82 | TMPRSS4 (1.00) | TMPRSS4KCNMA1P2RX1P2RX4P2RX7 | |
| SCHEMBL330431 | 0.81 | KCNMA1 (0.72) | TMPRSS4KCNMA1P2RX1P2RX4P2RX7 | |
| SCHEMBL28567056 | 0.79 | TMPRSS4 (0.61) | TMPRSS4KCNMA1P2RX1P2RX4P2RX7 | |
| SCHEMBL30216762 | 0.79 | TMPRSS4 (0.61) | TMPRSS4KCNMA1P2RX1P2RX4P2RX7 | |
| SCHEMBL14886092 | 0.78 | KCNMA1 (1.00) | TMPRSS4KCNMA1P2RX1P2RX4P2RX7 | |
| SCHEMBL11932152 | 0.78 | P2RX1 (1.00) | TMPRSS4KCNMA1P2RX1P2RX4P2RX7 | |
| SCHEMBL3512308 | 0.78 | TYK2 (1.00) | JAK2TYK2 | |
| SCHEMBL17770404 | 0.77 | P2RX1 (0.68) | TMPRSS4KCNMA1P2RX1P2RX4P2RX7 | |
| SCHEMBL30503640 | 0.77 | P2RX1 (0.68) | TMPRSS4KCNMA1P2RX1P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812056-B | N-pyridine-4-yl benzamide Cdc37 inhibitor and derivative and application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-112812056-A | N-pyridin-4-ylbenzamide Cdc37 inhibitors, derivatives thereof and uses thereof | 中国药科大学 | 2021-05-18 | — | — | CN | disclosed |