Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 13/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852505 | 0.93 | ABCB1 (0.48) | CCR1CNR1NPSR1HSP90AA1MAPT | |
| SCHEMBL2854340 | 0.92 | CCR1 (0.53) | CCR1CNR1NPSR1HSP90AA1MAPT | |
| SCHEMBL2863198 | 0.92 | CCR1 (0.50) | CCR1CNR1NPSR1MAPTTRPV1 | |
| SCHEMBL2857238 | 0.91 | CCR1 (0.43) | CCR1CNR1NPSR1HSP90AA1MAPT | |
| SCHEMBL2858011 | 0.91 | ABCB1 (0.51) | CCR1CNR1NPSR1HSP90AA1MAPT | |
| SCHEMBL2849956 | 0.91 | CCR1 (0.62) | CCR1NPSR1HSP90AA1MAPT | |
| SCHEMBL2855547 | 0.90 | TAAR1 (0.54) | CCR1CNR1NPSR1HSP90AA1MAPT | |
| SCHEMBL2863131 | 0.89 | CNR1 (0.50) | CCR1CNR1NPSR1HSP90AA1MAPT | |
| SCHEMBL2860669 | 0.89 | TAAR1 (0.46) | CCR1CNR1MAPTTAAR1KDM4E | |
| SCHEMBL2860847 | 0.88 | CCR1 (0.55) | CCR1CNR1NPSR1HSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |