Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 3/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850857 | 0.96 | TP53 (0.46) | TAAR1CNR1MAPTLMNATP53 | |
| SCHEMBL2860458 | 0.96 | TP53 (0.46) | TAAR1CNR1MAPTLMNATP53 | |
| SCHEMBL2850618 | 0.96 | MAPT (0.44) | TAAR1CNR1MAPTLMNACCR1 | |
| SCHEMBL2857768 | 0.95 | CNR1 (0.43) | TAAR1CNR1MAPTLMNACCR1 | |
| SCHEMBL2859861 | 0.95 | TAAR1 (0.51) | TAAR1CNR1MAPTLMNATP53 | |
| SCHEMBL2855547 | 0.95 | TAAR1 (0.54) | TAAR1CNR1MAPTLMNACCR1 | |
| SCHEMBL2860468 | 0.94 | KDM4E (0.44) | TAAR1CNR1MAPTLMNACCR1 | |
| SCHEMBL2852524 | 0.93 | TAAR1 (0.45) | TAAR1CNR1MAPTLMNAABCB1 | |
| SCHEMBL2853462 | 0.92 | TRPV1 (0.42) | TAAR1CNR1MAPTCCR1P2RX7 | |
| SCHEMBL2852839 | 0.91 | SLC7A5 (0.40) | TAAR1MAPTLMNACCR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |