Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852375 | 0.92 | CCR1 (0.63) | CCR1MAPTNPSR1HSP90AA1 | |
| SCHEMBL2850361 | 0.89 | ABCB1 (0.48) | MAPTCNR1 | |
| SCHEMBL2852485 | 0.89 | ABCB1 (0.50) | CCR1MAPTNPSR1HSP90AA1CNR1 | |
| SCHEMBL2857735 | 0.88 | CCR1 (0.54) | CCR1MAPTNPSR1HSP90AA1CNR1 | |
| SCHEMBL2860461 | 0.86 | TAAR1 (0.54) | MAPTCNR1 | |
| SCHEMBL2853116 | 0.86 | CNR1 (0.51) | MAPTCNR1 | |
| SCHEMBL2856900 | 0.85 | MAPT (0.47) | MAPTNPSR1CNR1 | |
| SCHEMBL2853390 | 0.85 | CCR1 (0.49) | CCR1MAPTNPSR1HSP90AA1KDM4E | |
| SCHEMBL2854459 | 0.84 | CCR1 (0.54) | CCR1MAPT | |
| SCHEMBL2860396 | 0.84 | GAA (0.52) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |