Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.43 |
| ▸ | CTSL | P07711 | 8/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572642 | 0.82 | KDM1A (0.41) | CTSS | |
| SCHEMBL16563814 | 0.82 | CTSS (0.40) | CTSSCTSLKCNH2SCN9ASCN5A | |
| SCHEMBL16563415 | 0.76 | PDE2A (0.50) | CTSSCTSLKCNH2SCN9ASCN5A | |
| SCHEMBL28568405 | 0.73 | MEN1 (0.38) | MEN1KMT2ACCR5 | |
| SCHEMBL16563264 | 0.71 | EPHX2 (0.38) | CTSSKCNH2 | |
| SCHEMBL23159239 | 0.71 | SLC7A5 (0.49) | SLC7A5MEN1KMT2ACCR5EPHX1 | |
| SCHEMBL17071853 | 0.71 | SLC7A5 (0.49) | SLC7A5MEN1KMT2ACCR5EPHX1 | |
| SCHEMBL6267837 | 0.70 | HTR2A (0.44) | — | |
| SCHEMBL20277947 | 0.69 | CTSS (0.43) | CTSSCTSLKCNH2SCN9ASCN5A | |
| SCHEMBL28567252 | 0.69 | CTSS (0.32) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109320481-B | Carboxylic acid NHPI ester decarboxylation alkylation method and application thereof in synthesis of diaryl derivatives | 南京大学 | 2021-01-12 | — | — | CN | disclosed |