SCHEMBL28577474

SCHEMBL28577474

COCCc1ccc(Oc2ccc(CCOC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.53
ACACA Q13085 1/20 0.53
PTPN1 P18031 2/20 0.47
NR3C1 P04150 1/20 0.46
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
CYP2D6 P10635 1/20 0.46
ADRA1A P35348 1/20 0.46
CYP2J2 P51589 1/20 0.46
PDE4D Q08499 1/20 0.46
ENPP2 Q13822 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
FFAR1 O14842 1/20 0.42
PPARG P37231 1/20 0.41
ST14 Q9Y5Y6 1/20 0.41
CALM1 P0DP23 1/20 0.41
MAOB P27338 1/20 0.41
LTA4H P09960 1/20 0.40
IGF1R P08069 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1338713 0.87 NR3C1 (0.44) ACACBACACANR3C1ADRB2ADRB1
SCHEMBL792026 0.86 TAAR1 (0.61) ENPP2TAAR1CALM1MAOBLTA4H
SCHEMBL21752972 0.84 SRD5A2 (0.58) ACACBACACAFFAR1
SCHEMBL11490631 0.82 NR3C1 (0.44) ACACBACACANR3C1ADRB2ADRB1
SCHEMBL7931583 0.80 ENPP2 (0.45) ACACBACACAPTPN1NR3C1ADRB2
SCHEMBL10062559 0.80 NQO1 (0.58) ACACBNR3C1ADRB2ADRB1CYP2D6
SCHEMBL12926311 0.80 MAOB (0.48) ACACBACACAPTPN1NR3C1ADRB2
SCHEMBL21752976 0.79 SMN1; SMN2 (0.51) ACACBACACA
SCHEMBL29157777 0.79 PPARA (0.42) ACACBACACANR3C1ADRB2ADRB1
SCHEMBL18595290 0.79 POLB (0.50) ACACBACACANR3C1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108640821-B Efficient and continuous p-chlorophenyl tert-butyl ether synthesis method and device 恒河材料科技股份有限公司 2021-06-18 CN disclosed