Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 3/20 | 0.60 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.60 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.60 |
| ▸ | GSK3B | P49841 | 7/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.49 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.49 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069602 | 0.88 | JAK2 (0.51) | PRKAG1PRKAA1PRKAB1NTRK1PRKAB2 | |
| SCHEMBL17324787 | 0.86 | PRKAG1 (0.62) | PRKAG1PRKAA1PRKAB1GSK3BROCK1 | |
| SCHEMBL929332 | 0.86 | PRKAG1 (0.79) | PRKAG1PRKAA1PRKAB1GSK3BROCK1 | |
| SCHEMBL4794844 | 0.85 | KDM4E (0.63) | PRKAG1PRKAA1PRKAB1GSK3BROCK1 | |
| SCHEMBL17321404 | 0.82 | PRKAG1 (0.58) | PRKAG1PRKAA1PRKAB1GSK3BROCK1 | |
| SCHEMBL27837474 | 0.81 | NTRK1 (0.44) | PRKAG1PRKAA1PRKAB1GSK3BNTRK1 | |
| SCHEMBL2436313 | 0.80 | KDM4E (0.55) | PRKAG1PRKAA1PRKAB1TTKKDM4E | |
| SCHEMBL16099058 | 0.80 | PRKAG1 (0.55) | PRKAG1PRKAA1PRKAB1GSK3BROCK1 | |
| SCHEMBL31507475 | 0.80 | KDM4E (0.64) | PRKAG1PRKAA1PRKAB1GSK3BKDM4E | |
| SCHEMBL493081 | 0.80 | KDM4E (0.64) | PRKAG1PRKAA1PRKAB1GSK3BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805282-A | Indazole-carboxamide derivatives and uses thereof | 广东东阳光药业有限公司 | 2021-05-14 | — | — | CN | disclosed |