Norleucine

Norleucine

SCHEMBL28577914

CCCCC(N)C(=O)O.O=C1CCC(=O)N1O

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 3/20 0.48
SLC1A2 P43004 2/20 0.47
SLC1A1 P43005 2/20 0.47
SLC1A3 P43003 1/20 0.47
NOS1 P29475 5/20 0.45
NOS2 P35228 4/20 0.42
GRIK1 P39086 3/20 0.42
CYP2C19 P33261 3/20 0.42
NOS3 P29474 3/20 0.42
GRIK2 Q13002 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
METAP1 P53582 1/20 0.42
GSR P00390 1/20 0.42
CYP1A2 P05177 1/20 0.41
GLA P06280 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
APEX1 P27695 1/20 0.41
NOD1 Q9Y239 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysine SCHEMBL1273912 0.84 GSR (0.65) NOS1NOS2CYP2C19NOS3MEN1
Lysine SCHEMBL2635126 0.84 GSR (0.65) NOS1NOS2CYP2C19NOS3MEN1
Lysine SCHEMBL17275081 0.83 GSR (0.62) NOS1NOS2CYP2C19NOS3MEN1
Norleucine SCHEMBL198127 0.80
Norleucine SCHEMBL5051846 0.80 SLC1A2 (0.67) DDAH1SLC1A2SLC1A1SLC1A3NOS1
Norleucine SCHEMBL5497693 0.80 SLC1A2 (0.67) DDAH1SLC1A2SLC1A1SLC1A3NOS1
Norleucine SCHEMBL2785913 0.80 SLC1A2 (0.67) DDAH1SLC1A2SLC1A1SLC1A3NOS1
Norleucine SCHEMBL8392 0.80
Norleucine SCHEMBL26474 0.80 SLC1A2 (0.67) DDAH1SLC1A2SLC1A1SLC1A3NOS1
Norleucine SCHEMBL8393 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112218640-A Nucleotide analogs and their use in nucleic acid sequencing and analysis 哥伦比亚大学董事会 2021-01-12 CN disclosed