Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394029 | 0.84 | CHRNB2 (0.44) | CNR1FAAHSOAT1KMT2AMEN1 | |
| SCHEMBL21702922 | 0.84 | PPARG (0.48) | FAAHKMT2AMEN1TP53CYP1A2 | |
| SCHEMBL4572723 | 0.82 | CHRNB2 (0.46) | FAAHSOAT1KMT2AMEN1TP53 | |
| SCHEMBL31253415 | 0.81 | CNR1 (0.49) | CNR1FAAHSOAT1KMT2AMEN1 | |
| SCHEMBL23139471 | 0.79 | CHRNB2 (0.47) | CYP1A2CYP2C19CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29498992 | 0.79 | CHRNB2 (0.47) | CYP1A2CYP2C19CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8936205 | 0.79 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL13058103 | 0.77 | CNR1 (0.47) | CNR1FAAHSOAT1KMT2AMEN1 | |
| SCHEMBL30203270 | 0.76 | CNR1 (0.50) | CNR1FAAHSOAT1KMT2AMEN1 | |
| SCHEMBL8699814 | 0.76 | PPARG (0.51) | FAAHSOAT1KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112789040-A | Transglutaminase 2(TG2) inhibitors | 思达利医药公司 | 2021-05-11 | — | — | CN | claimed |
| CN-112789040-A | Transglutaminase 2(TG2) inhibitors | 思达利医药公司 | 2021-05-11 | — | — | CN | disclosed |