Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394029 | 0.92 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL29462203 | 0.87 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL167052 | 0.81 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL4417283 | 0.80 | ALDH1A1 (0.30) | ALDH1A1MAPT | |
| SCHEMBL28577936 | 0.79 | CNR1 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL5176271 | 0.79 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL4779558 | 0.79 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL1029179 | 0.79 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL12252969 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL18813838 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510530-A | WHEN POLYMERIZED GIVE OPTICALLY ACTIVE POLYMERS WHICH ARE USEFUL AS ADSORBENTS FOR CHROMATOGRAPHIC SEPARATION OF RACEMATES INTO ENANTIOMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| US-5432251-A | Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| US-5432252-A | Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| US-5347042-A | Optically active sulphur-containing amino acid derivatives, their preparation, their polymerisation to give optically active polymers and the use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1994-09-13 | — | — | US | disclosed |
| US-5281750-A | Deracemization and optical inversion using polymer supports | RHONE-POULENC CHIMIE (FR) | 1994-01-25 | — | — | US | disclosed |