SCHEMBL28577940

SCHEMBL28577940

CC(CCCC(N)=O)=C(C)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 2/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
FAAH O00519 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALOX15 P16050 2/20 0.33
BLM P54132 2/20 0.33
PMP22 Q01453 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.33
CNR1 P21554 1/20 0.32
KDM4E B2RXH2 2/20 0.31
PAOX Q6QHF9 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6556056 0.83 PAOX (0.44) KMT2AMEN1CYP1A2ALOX15BLM
SCHEMBL28779585 0.83 CES1 (0.46) SOAT1KMT2AMEN1FAAHTP53
SCHEMBL20531039 0.79 CES2 (0.50) SOAT1KMT2AMEN1FAAHTP53
SCHEMBL29116602 0.79 CES2 (0.50) SOAT1KMT2AMEN1FAAHTP53
Hydrochloric Acid SCHEMBL30177594 0.79 PAOX (0.52) KMT2AMEN1CYP1A2ALOX15BLM
SCHEMBL29161903 0.79 CES2 (0.50) SOAT1KMT2AMEN1FAAHTP53
Hydrochloric Acid SCHEMBL30685507 0.79 PAOX (0.52) KMT2AMEN1CYP1A2ALOX15BLM
SCHEMBL16056498 0.77 CES1 (0.41) SOAT1KMT2AMEN1FAAHTP53
SCHEMBL8762445 0.77 ALDH1A1 (0.53) ALOX15BLMPMP22TDP1LMNA
SCHEMBL1720977 0.77 CES1 (0.41) SOAT1KMT2AMEN1FAAHTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112789040-A Transglutaminase 2(TG2) inhibitors 思达利医药公司 2021-05-11 CN claimed
CN-112789040-A Transglutaminase 2(TG2) inhibitors 思达利医药公司 2021-05-11 CN disclosed