SCHEMBL28577973

SCHEMBL28577973

COc1cccc(C=C(C=O)c2ccccc2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.65
MEN1 O00255 1/20 0.65
ALDH1A1 P00352 1/20 0.65
NQO2 P16083 1/20 0.61
BCHE P06276 1/20 0.57
MAOB P27338 2/20 0.54
MAPT P10636 1/20 0.53
TUBB4A P04350 1/20 0.49
TUBB P07437 1/20 0.49
TUBA3C P0DPH7 1/20 0.49
TUBA1B P68363 1/20 0.49
TUBA4A P68366 1/20 0.49
TUBB4B P68371 1/20 0.49
TUBB3 Q13509 1/20 0.49
TUBB2A Q13885 1/20 0.49
TUBB8 Q3ZCM7 1/20 0.49
TUBA3E Q6PEY2 1/20 0.49
TUBA1A Q71U36 1/20 0.49
TUBA1C Q9BQE3 1/20 0.49
TUBB6 Q9BUF5 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31452298 0.91 KMT2A (0.57) KMT2AMEN1ALDH1A1NQO2BCHE
SCHEMBL10399039 0.86 NFE2L2 (0.56) KMT2AMEN1ALDH1A1NQO2BCHE
SCHEMBL10399043 0.86 NFE2L2 (0.56) KMT2AMEN1ALDH1A1NQO2BCHE
SCHEMBL19112441 0.84 NQO2 (0.57) KMT2AMEN1ALDH1A1NQO2MAOB
SCHEMBL527100 0.83 NQO2 (0.71) KMT2AMEN1ALDH1A1NQO2BCHE
SCHEMBL27725904 0.83 NQO2 (0.67) KMT2AMEN1ALDH1A1NQO2BCHE
SCHEMBL10669156 0.83 NQO2 (0.71) KMT2AMEN1ALDH1A1NQO2BCHE
SCHEMBL18889744 0.81 NQO2 (0.56) KMT2AMEN1ALDH1A1NQO2TUBB4A
SCHEMBL18889747 0.81 NQO2 (0.56) KMT2AMEN1ALDH1A1NQO2TUBB4A
SCHEMBL3406654 0.81 MEN1 (0.59) KMT2AMEN1ALDH1A1BCHEMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113072536-B Method for preparing 2-phenyl-3-benzoyl benzodihydrogen selenium substituted pyridine compound without metal catalysis 浙江农林大学暨阳学院 2021-11-23 CN disclosed
CN-113072536-A Method for preparing 2-phenyl-3-benzoyl benzodihydrogen selenium substituted pyridine compound without metal catalysis 浙江农林大学暨阳学院 2021-07-06 CN disclosed