Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399039 | 1.00 | NFE2L2 (0.56) | NFE2L2NPC1RAB9ANQO2ALDH1A1 | |
| SCHEMBL28577973 | 0.86 | KMT2A (0.65) | NPC1RAB9ANQO2ALDH1A1MEN1 | |
| SCHEMBL31452298 | 0.83 | KMT2A (0.57) | NPC1RAB9ANQO2ALDH1A1MEN1 | |
| SCHEMBL19112441 | 0.82 | NQO2 (0.57) | NPC1RAB9ANQO2ALDH1A1MEN1 | |
| SCHEMBL18889747 | 0.80 | NQO2 (0.56) | NPC1RAB9ANQO2ALDH1A1MEN1 | |
| SCHEMBL18889744 | 0.80 | NQO2 (0.56) | NPC1RAB9ANQO2ALDH1A1MEN1 | |
| SCHEMBL14692567 | 0.76 | BCHE (0.75) | NFE2L2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL10399041 | 0.76 | BCHE (0.75) | NFE2L2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL27575136 | 0.74 | CES2 (0.53) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL9507267 | 0.74 | KMT2A (0.55) | NFE2L2NPC1RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |