Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761335 | 0.82 | ADRA2C (0.51) | NPC1TSHRSMN1; SMN2MAPK1AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL5104669 | 0.79 | NPC1 (0.79) | NPC1TSHRSMN1; SMN2USP2KDM4E | |
| SCHEMBL18600532 | 0.79 | CYP1A2 (0.50) | TSHRSMN1; SMN2MAPK1AKR1C3USP2 | |
| SCHEMBL614496 | 0.79 | AKR1C3 (0.58) | NPC1TSHRMAPK1AKR1C3KMT2A | |
| SCHEMBL21393223 | 0.78 | NPC1 (0.62) | NPC1TSHRSMN1; SMN2PARP1KMT2A | |
| SCHEMBL3654065 | 0.77 | NPC1 (0.96) | NPC1TSHRSMN1; SMN2MAPK1USP2 | |
| SCHEMBL17009548 | 0.77 | NPC1 (0.89) | NPC1TSHRSMN1; SMN2USP2KDM4E | |
| SCHEMBL31565663 | 0.77 | NPC1 (0.96) | NPC1TSHRSMN1; SMN2MAPK1USP2 | |
| SCHEMBL6159637 | 0.77 | NPC1 (0.57) | NPC1SMN1; SMN2PARP1MAPTLMNA | |
| SCHEMBL3081421 | 0.76 | NPC1 (0.70) | NPC1MAPK1PARP1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112888681-A | Tropomyosin Receptor Kinase (TRK) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2021-06-01 | — | — | CN | disclosed |