Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600369 | 0.87 | KCNMA1 (0.67) | KCNMA1ALDH1A1PKMMAPTTDP1 | |
| SCHEMBL6815623 | 0.84 | KCNMA1 (0.77) | KCNMA1ALDH1A1PKMMAPTTDP1 | |
| SCHEMBL29886399 | 0.84 | KCNMA1 (0.77) | KCNMA1ALDH1A1PKMMAPTTDP1 | |
| SCHEMBL28589555 | 0.82 | MAPT (0.54) | KCNMA1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29168827 | 0.81 | KCNMA1 (0.78) | KCNMA1ALDH1A1PKMMAPTTDP1 | |
| SCHEMBL18177864 | 0.80 | PKM (0.67) | KCNMA1ALDH1A1PKMMAPTTDP1 | |
| SCHEMBL2060577 | 0.80 | KCNMA1 (0.73) | KCNMA1ALDH1A1PKMMAPTTDP1 | |
| SCHEMBL28579644 | 0.80 | KCNMA1 (0.70) | KCNMA1ALDH1A1PKMMAPTTDP1 | |
| SCHEMBL29886218 | 0.80 | KCNMA1 (0.77) | KCNMA1ALDH1A1PKMMAPTTDP1 | |
| SCHEMBL16592539 | 0.80 | KCNMA1 (0.77) | KCNMA1ALDH1A1PKMMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061098-B | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113061098-A | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-07-02 | — | — | CN | disclosed |