Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.83 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.81 |
| ▸ | ALK | Q9UM73 | 13/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28595246 | 0.94 | MAPK3 (0.81) | EGFRMAPK3ALK | |
| SCHEMBL28053891 | 0.92 | JAK3 (0.77) | EGFRMAPK3ALK | |
| SCHEMBL2724456 | 0.91 | EGFR (1.00) | EGFRMAPK3ALK | |
| SCHEMBL28589814 | 0.91 | EGFR (0.94) | EGFRMAPK3ALK | |
| SCHEMBL28053865 | 0.90 | EGFR (0.83) | EGFRMAPK3ALK | |
| SCHEMBL28053991 | 0.90 | JAK3 (0.73) | EGFRMAPK3ALK | |
| Hydrochloric Acid SCHEMBL28053870 | 0.89 | EGFR (0.82) | EGFRMAPK3ALK | |
| SCHEMBL15938213 | 0.89 | MAPK3 (1.00) | EGFRMAPK3ALK | |
| SCHEMBL28589279 | 0.88 | ALK (0.71) | EGFRMAPK3ALK | |
| SCHEMBL16769540 | 0.88 | ALK (1.00) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905245-B | 2, 4-disubstituted pyrimidines | 正大天晴药业集团股份有限公司 | 2021-06-25 | — | — | CN | disclosed |