Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.52 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23534299 | 0.82 | L3MBTL1 (0.49) | USP30PARP1MEN1ALDH1A1KMT2A | |
| SCHEMBL28581769 | 0.82 | L3MBTL1 (0.52) | USP30PARP1MEN1ALDH1A1KMT2A | |
| SCHEMBL28923421 | 0.81 | USP30 (0.56) | USP30PARP1MEN1ALDH1A1KMT2A | |
| SCHEMBL25192922 | 0.81 | USP30 (0.56) | USP30PARP1MEN1ALDH1A1KMT2A | |
| SCHEMBL12127425 | 0.81 | KDM4E (0.49) | USP30ALDH1A1KDM4EFPR2POLB | |
| SCHEMBL29176342 | 0.80 | KMT2A (0.55) | MEN1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL25206972 | 0.79 | USP30 (0.52) | USP30PARP1MEN1KMT2AFPR3 | |
| SCHEMBL29176340 | 0.79 | ALDH1A1 (0.54) | MEN1ALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL23533928 | 0.78 | USP30 (0.54) | USP30PARP1MEN1ALDH1A1KMT2A | |
| SCHEMBL25337397 | 0.77 | BACE1 (0.50) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955450-A | Substituted indole and indazole compounds | 百时美施贵宝公司 | 2021-06-11 | — | — | CN | disclosed |