Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.36 |
| ▸ | QPCT | Q16769 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583235 | 0.95 | MEN1 (0.40) | MEN1KMT2AGRM2ADAMTS5QPCT | |
| SCHEMBL28582761 | 0.94 | MEN1 (0.39) | MEN1KMT2AGRM2ADAMTS5QPCT | |
| SCHEMBL28582759 | 0.94 | MEN1 (0.39) | MEN1KMT2AGRM2ADAMTS5QPCT | |
| SCHEMBL26813648 | 0.86 | CPB2 (0.42) | MEN1KMT2AGRM2ADAMTS5QPCT | |
| SCHEMBL26813651 | 0.86 | CPB2 (0.45) | MEN1KMT2AGRM2ADAMTS5QPCT | |
| SCHEMBL5726708 | 0.85 | CPB2 (0.45) | MEN1KMT2AGRM2SMYD3CPB2 | |
| SCHEMBL24842023 | 0.84 | MEN1 (0.40) | MEN1KMT2AGRM2ADAMTS5QPCT | |
| SCHEMBL24842800 | 0.84 | MEN1 (0.40) | MEN1KMT2AGRM2ADAMTS5QPCT | |
| SCHEMBL2282033 | 0.83 | CPB2 (0.45) | MEN1KMT2AGRM2ADAMTS5MAPK1 | |
| SCHEMBL15775548 | 0.81 | MEN1 (0.43) | MEN1KMT2AGRM2ADAMTS5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336944-B | Tripterine imidazole derivative and preparation method and application thereof | 中国药科大学 | 2021-04-27 | — | — | CN | disclosed |