Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.36 |
| ▸ | QPCT | Q16769 | 3/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28582761 | 0.99 | MEN1 (0.39) | MEN1KMT2AMAPK1GRM2ADAMTS5 | |
| SCHEMBL28582759 | 0.99 | MEN1 (0.39) | MEN1KMT2AMAPK1GRM2ADAMTS5 | |
| SCHEMBL28579686 | 0.95 | MEN1 (0.41) | MEN1KMT2AMAPK1GRM2ADAMTS5 | |
| SCHEMBL5726708 | 0.87 | CPB2 (0.45) | MEN1KMT2AGRM2CPB2CPB1 | |
| SCHEMBL24842023 | 0.85 | MEN1 (0.40) | MEN1KMT2AMAPK1GRM2ADAMTS5 | |
| SCHEMBL24842800 | 0.85 | MEN1 (0.40) | MEN1KMT2AMAPK1GRM2ADAMTS5 | |
| SCHEMBL26813648 | 0.85 | CPB2 (0.42) | MEN1KMT2AMAPK1GRM2ADAMTS5 | |
| SCHEMBL26813651 | 0.85 | CPB2 (0.45) | MEN1KMT2AGRM2ADAMTS5QPCT | |
| SCHEMBL2282033 | 0.81 | CPB2 (0.45) | MEN1KMT2AMAPK1GRM2ADAMTS5 | |
| SCHEMBL15775548 | 0.80 | MEN1 (0.43) | MEN1KMT2AMAPK1GRM2ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336944-B | Tripterine imidazole derivative and preparation method and application thereof | 中国药科大学 | 2021-04-27 | — | — | CN | disclosed |