Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585580 | 0.86 | HPGD (0.48) | MAPTMAPK1GFERHPGDRAB9A | |
| SCHEMBL28588645 | 0.84 | MAPT (0.39) | MAPTMAPK1GFERHPGDRAB9A | |
| SCHEMBL28578241 | 0.83 | RORC (0.49) | MAPTMAPK1GFERHPGDRAB9A | |
| SCHEMBL17711525 | 0.80 | HPGD (0.47) | HPGDRAB9AALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL17761016 | 0.79 | HPGD (0.46) | HPGDRAB9AALDH1A1CNR2HSD17B10 | |
| SCHEMBL28585047 | 0.77 | RORC (0.50) | MAPTMAPK1GFERRAB9AALDH1A1 | |
| SCHEMBL17711415 | 0.75 | HPGD (0.40) | HPGDRAB9AALDH1A1CNR2HSD17B10 | |
| SCHEMBL17716662 | 0.75 | MAPT (0.50) | MAPTMAPK1GFERHPGDRAB9A | |
| SCHEMBL17717309 | 0.75 | MAPT (0.50) | MAPTMAPK1GFERHPGDRAB9A | |
| SCHEMBL28588701 | 0.74 | MAPT (0.49) | MAPTMAPK1GFERHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979630-A | Trifluoromethanols as Ror gamma t modulators | 詹森药业有限公司 | 2021-06-18 | — | — | CN | disclosed |