SCHEMBL28580381

SCHEMBL28580381

Sc1ccccc1-c1ccc(Br)cc1I

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 2/20 0.46
CYP2A6 P11509 2/20 0.34
PDK2 Q15119 1/20 0.34
MAPK1 P28482 3/20 0.33
CYP1A2 P05177 2/20 0.33
S100A4 P26447 1/20 0.33
MAOB P27338 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
BCL2 P10415 1/20 0.32
MCL1 Q07820 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 2/20 0.32
AHR P35869 1/20 0.31
IDO1 P14902 1/20 0.31
BACE1 P56817 1/20 0.31
CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2848829 0.81 CYP2A6 (0.47) PTPRCCYP2A6MAPK1S100A4TDP1
SCHEMBL29279869 0.77 PTPRC (0.46) PTPRCCYP2A6PDK2MAPK1CYP1A2
SCHEMBL19180559 0.77 PTPRC (0.46) PTPRCCYP2A6PDK2MAPK1CYP1A2
SCHEMBL28837915 0.77 PTPRC (0.46) PTPRCCYP2A6PDK2MAPK1CYP1A2
SCHEMBL28723244 0.77 IDO1 (0.42) PTPRCMAPK1S100A4MEN1NPC1
SCHEMBL1957175 0.74 ALDH1A1 (0.52) PTPRCCYP2A6MAPK1TDP1NPC1
SCHEMBL28923513 0.73 PTPRC (0.46) PTPRCCYP2A6MAPK1CYP1A2TDP1
SCHEMBL29290421 0.73 PTPRC (0.46) PTPRCCYP2A6PDK2MAPK1CYP1A2
SCHEMBL8588230 0.73 ALDH1A1 (0.50) PTPRCCYP2A6MAPK1MAOBTDP1
SCHEMBL28580714 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113045553-A Aza-aromatic compound used as electron transport material and application thereof 烟台显华化工科技有限公司 2021-06-29 CN disclosed