SCHEMBL2848829

SCHEMBL2848829

Brc1ccc(-c2ccc(Br)cc2I)c(I)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.47
S100A4 P26447 1/20 0.46
PTPRC P08575 1/20 0.39
BCL2 P10415 2/20 0.38
MCL1 Q07820 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 4/20 0.36
ALOX15 P16050 3/20 0.36
MAPK1 P28482 3/20 0.36
AHR P35869 1/20 0.36
HSP90AA1 P07900 1/20 0.35
TLR9 Q9NR96 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
METAP1 P53582 1/20 0.34
CHEK1 O14757 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30558020 0.87 S100A4 (0.41) CYP2A6S100A4PTPRCBCL2MCL1
SCHEMBL14906928 0.87 S100A4 (0.41) CYP2A6S100A4PTPRCBCL2MCL1
SCHEMBL20565647 0.87 S100A4 (0.41) CYP2A6S100A4PTPRCBCL2MCL1
SCHEMBL22884437 0.86 DHODH (0.38) CYP2A6S100A4PTPRCALDH1A1AHR
SCHEMBL1957175 0.81 ALDH1A1 (0.52) CYP2A6PTPRCALDH1A1MAPK1TDP1
SCHEMBL28580381 0.81 PTPRC (0.46) CYP2A6S100A4PTPRCBCL2MCL1
SCHEMBL29645435 0.79
SCHEMBL5469035 0.79
SCHEMBL29417946 0.77
SCHEMBL2713465 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2578592-B1 QUINOID SILAFLUORENE ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND USE THEREOF OCEAN S KING LIGHTING SCIENCE&TECHNOLOGY CO LTD (CN) 2016-07-13 EP claimed
US-8481754-B2 Quinoid silafluorene organic semiconductor material, preparation method and use thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-07-09 US claimed
US-20130072693-A1 QUINOID SILAFLUORENE ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND USE THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-03-21 US claimed
US-20250212684-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, COMPOUND, AND MANUFACTURING METHOD OF COMPOUND FUJIFILM CORPORATION (JP) 2025-06-26 US disclosed
WO-2024071143-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, LIGHT SENSOR, COMPOUND, AND COMPOUND PRODUCTION METHOD 富士フイルム株式会社 2024-04-04 WO disclosed
CN-109970791-B Indenotriphenylene derivative and organic electroluminescent device using the same 机光科技股份有限公司 2022-07-22 CN disclosed
US-11316118-B2 Dibenzo[d,B]silole-based reactive mesogens LOMOX LIMITED (GB) 2022-04-26 US disclosed
US-11316118-B2 Dibenzo[d,B]silole-based reactive mesogens LOMOX LIMITED (GB) 2022-04-26 US disclosed
US-11183648-B2 Polymers, their preparation and uses CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2021-11-23 US disclosed
US-11183648-B2 Polymers, their preparation and uses CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2021-11-23 US disclosed
EP-3523313-B1 DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS LOMOX LTD (GB) 2021-05-05 EP disclosed
US-20070282094-A1 Silole-based polymers and semiconductor materials prepared from the same USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2007-12-06 US disclosed
US-20070282094-A1 Silole-based polymers and semiconductor materials prepared from the same USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2007-12-06 US disclosed
US-20070282094-A1 Silole-based polymers and semiconductor materials prepared from the same USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2007-12-06 US disclosed
WO-2007133705-A2 SILOLE-BASED POLYMERS AND SEMICONDUCTOR MATERIALS PREPARED FROM THE SAME NORTHWESTERN UNIVERSITY (US) 2007-11-22 WO disclosed
US-20070248839-A1 Dibenzosilol Polymers, Their Preparation and Uses CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-25 US disclosed
US-20070248839-A1 Dibenzosilol Polymers, Their Preparation and Uses CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-25 US disclosed
US-20070248839-A1 Dibenzosilol Polymers, Their Preparation and Uses CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-25 US disclosed
EP-1682600-A1 DIBENZOSILOL POLYMERS, THEIR PREPARATION AND USES Cambridge Display Technology Limited (GB) 2006-07-26 EP disclosed
WO-2005047363-A1 DIBENZOSILOL POLYMERS, THEIR PREPARATION AND USES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2005-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11316118-B2 Dibenzo[d,B]silole-based reactive mesogens CCNB1, CCNE2, UBE2G2 CYP2A6 221/4885S100A4 3751/4885PTPRC 4012/4885
US-20250212684-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, COMPOUND, AND MANUFACTURING METHOD OF COMPOUND CRY1, CRY2, PRDM9 CYP2A6 907/4885S100A4 745/4885PTPRC 4640/4885
US-11183648-B2 Polymers, their preparation and uses PARG, PARP1, PCBP1 CYP2A6 4693/4885S100A4 3127/4885PTPRC 2712/4885
US-20130072693-A1 QUINOID SILAFLUORENE ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND USE THEREOF RPS4Y1, OR10J3, C5 CYP2A6 3333/4885S100A4 714/4885PTPRC 2277/4885
US-20070248839-A1 Dibenzosilol Polymers, Their Preparation and Uses PARG, PCBP1, RAD54L CYP2A6 4055/4885S100A4 4280/4885PTPRC 3504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.