Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16648981 | 0.90 | KMT2A (0.44) | TSHRKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL472109 | 0.81 | KMT2A (0.41) | TSHRKMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL16378090 | 0.77 | ALDH1A1 (0.49) | TSHRKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL11616058 | 0.77 | CYP4F2 (0.48) | TSHRKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL18989246 | 0.77 | TSHR (0.49) | TSHRKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL10424628 | 0.77 | CYP3A4 (0.38) | TSHRKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL10760634 | 0.76 | MEN1 (0.41) | KMT2AALDH1A1MEN1TAAR1MAPT | |
| SCHEMBL14262638 | 0.76 | MEN1 (0.42) | KMT2AALDH1A1MEN1MAPTHPGD | |
| SCHEMBL11700549 | 0.76 | CYP4F2 (0.47) | TSHRKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL988106 | 0.76 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1TAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |