Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22761305 | 0.84 | MAPT (0.69) | KMT2AMEN1MAPTSMN1; SMN2GFER | |
| SCHEMBL28565094 | 0.82 | MAPT (0.67) | KMT2AMEN1MAPTSMN1; SMN2GFER | |
| SCHEMBL28564131 | 0.82 | NPC1 (0.70) | KMT2AMEN1MAPTSMN1; SMN2GFER | |
| SCHEMBL28911498 | 0.82 | MAPT (0.68) | KMT2AMEN1MAPTSMN1; SMN2GFER | |
| SCHEMBL28030442 | 0.82 | MAPT (0.67) | KMT2AMEN1MAPTSMN1; SMN2GFER | |
| SCHEMBL28588005 | 0.82 | MAPT (0.74) | KMT2AMEN1MAPTSMN1; SMN2GFER | |
| SCHEMBL8172023 | 0.82 | RAB9A (0.70) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL14531681 | 0.82 | NPY5R (0.62) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL1302488 | 0.81 | MEN1 (0.96) | KMT2AMEN1MAPTSMN1; SMN2GFER | |
| SCHEMBL28911485 | 0.81 | ALOX5 (0.62) | KMT2AMEN1MAPTSMN1; SMN2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880786-B | Synthesis method and anti-oxidation application of camphene aldehyde thiazole hydrazone derivative | 江西农业大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-115448915-A | SIRT5 inhibitor and preparation method and application thereof | 广西师范大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-112939889-A | Fluorine-containing compound and application thereof as antifungal drug | 北京工商大学 | 2021-06-11 | — | — | CN | disclosed |