Dinitrophenylene

Dinitrophenylene

SCHEMBL28580588

CCOC(C)=O.O=[N+]([O-])c1cccc([N+](=O)[O-])c1.O=[N+]([O-])c1cccc([N+](=O)[O-])c1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.59
LMNA P02545 3/20 0.57
TSHR P16473 2/20 0.57
ALDH1A1 P00352 2/20 0.56
GAA P10253 1/20 0.55
KMT2A Q03164 5/20 0.54
MEN1 O00255 4/20 0.54
CACNA1F O60840 2/20 0.54
CACNA1D Q01668 2/20 0.54
CACNA1S Q13698 2/20 0.54
CACNA1C Q13936 2/20 0.54
ADORA3 P0DMS8 1/20 0.54
NPC1 O15118 1/20 0.54
HSP90AA1 P07900 1/20 0.54
PKM P14618 1/20 0.54
HPGD P15428 1/20 0.54
CCR6 P51684 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
APOBEC3G Q9HC16 1/20 0.54
CES2 O00748 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinitrophenylene SCHEMBL27521455 1.00 GLO1 (0.59) GLO1LMNATSHRALDH1A1GAA
Ethyl Acetate SCHEMBL10515029 0.88 ALDH1A1 (0.59) LMNAALDH1A1GAAKMT2AMEN1
Nitrobenzene SCHEMBL9326043 0.88 ALDH1A1 (0.55) GLO1LMNAALDH1A1GAAKMT2A
Dinitrophenylene SCHEMBL27988648 0.83 MAPT (0.55) GLO1LMNATSHRALDH1A1GAA
Dinitrophenylene SCHEMBL27790604 0.83 GLO1 (0.55) GLO1LMNATSHRALDH1A1GAA
Dinitrophenylene SCHEMBL27724274 0.82 TSHR (0.77) GLO1LMNATSHRALDH1A1GAA
Nitrobenzene SCHEMBL27659769 0.81 ALDH1A1 (0.47) GLO1LMNAALDH1A1GAAKMT2A
SCHEMBL3388760 0.81 NPC1 (0.62) LMNAALDH1A1GAAKMT2AMEN1
SCHEMBL3719794 0.81 MAOB (0.63) LMNATSHRALDH1A1GAAKMT2A
Dinitrophenylene SCHEMBL9862221 0.80 TSHR (0.68) GLO1LMNATSHRALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-213528613-U Oil bath heating reaction kettle for producing ethyl bis (2, 4-dinitrobenzene) acetate 上海优合生物科技有限公司 2021-06-25 CN claimed