⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187410 | 0.97 | CA1 (0.55) | — | |
| SCHEMBL2442152 | 0.97 | — | — | |
| Methane SCHEMBL27649004 | 0.94 | CA1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL11848293 | 0.94 | CA1 (0.52) | — | |
| Azepane SCHEMBL5822820 | 0.82 | CA2 (0.46) | — | |
| Piperidine SCHEMBL11805123 | 0.82 | CA2 (0.46) | — | |
| SCHEMBL28409402 | 0.81 | CA1 (0.44) | — | |
| SCHEMBL214633 | 0.79 | — | — | |
| SCHEMBL11464823 | 0.76 | — | — | |
| SCHEMBL11382430 | 0.76 | CA1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002516844-A | — | — | 2002-06-11 | — | — | JP | claimed |
| EP-0957913-A4 | N-LINKED SULFONAMIDES OF HETEROCYCLIC THIOESTERS | GUILFORD PHARM INC (US) | 2002-05-02 | — | — | EP | claimed |
| US-20020016341-A1 | Heterocyclic thioester and ketone hair growth compositions and uses | GPI NIL HOLDINGS, INC. | 2002-02-07 | — | — | US | claimed |
| EP-1104298-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-06 | — | — | EP | claimed |
| EP-1083873-A1 | HETEROCYCLIC THIOESTER AND KETONE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL Holdings, Inc. (US) | 2001-03-21 | — | — | EP | claimed |
| WO-2000009479-A2 | HETEROCYCLIC THIOESTERS OR KETONES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | claimed |
| WO-1999062488-A1 | HETEROCYCLIC THIOESTER AND KETONE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | claimed |
| EP-0957913-A1 | N-LINKED SULFONAMIDES OF HETEROCYCLIC THIOESTERS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-24 | — | — | EP | claimed |
| WO-1998029116-A1 | N-LINKED SULFONAMIDES OF HETEROCYCLIC THIOESTERS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-07-09 | — | — | WO | claimed |
| CN-108530636-B | Single functionalized branched polyethylene glycol | 厦门赛诺邦格生物科技股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-108530617-B | Branched polyethylene glycol heterobifunctional derivative, preparation method thereof and two-component bio-related substance conjugate thereof | 厦门赛诺邦格生物科技股份有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-110643032-A | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2020-01-03 | — | — | CN | disclosed |
| WO-2012149093-A1 | 2-GUANIDINO-4-OXO-IMIDAZOLINE DERIVATIVES AS ANTIMALARIAL AGENTS, SYNTHESIS AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF ARMY (US) | 2012-11-01 | — | — | WO | disclosed |
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-5637731-A | CHOLINERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5550257-A | TREATING CENTRAL CHOLINERGIC DYSFUNCTION | AMERICAN CYANAMID COMPANY (US) | 1996-08-27 | — | — | US | disclosed |
| US-4826852-A | Novel ergolinyl compounds nitrogen-substituted in the 8-position, useful for treating dopamine deficiency | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0082808-B1 | NOVEL ERGOLINYL COMPOUNDS NITROGEN-SUBSTITUTED IN THE 8-POSITION, THEIR PREPARATION, AND USE AS MEDICINAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-05-27 | — | — | EP | disclosed |
| US-4491465-A | Substituted phenyl (thiono)carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds | KURARAY CO., LTD. (JP) | 1985-01-01 | — | — | US | disclosed |
| US-3953427-A | Process for the preparation of substituted S-alkyl thio-carbamates | ESZAKMAGYARORSZAGI VEGYIMUVEK (HU) | 1976-04-27 | — | — | US | disclosed |