Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | S100A4 | P26447 | 4/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | TDP2 | O95551 | 3/20 | 0.59 |
| ▸ | CES1 | P23141 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PTPRC | P08575 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.59 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthraquinone SCHEMBL9174151 | 0.87 | MEN1 (0.75) | MAOAPOLBRECQLMEN1KMT2A | |
| Naphthoquinone SCHEMBL9246076 | 0.84 | MAOA (0.82) | MAOAPOLBRECQLMEN1KMT2A | |
| Naphthoquinone SCHEMBL9338926 | 0.84 | MAOA (0.82) | MAOAPOLBRECQLMEN1KMT2A | |
| Phthalic Anhydride SCHEMBL29134637 | 0.82 | TDP1 (0.78) | MAOAPOLBRECQLMEN1KMT2A | |
| SCHEMBL15525025 | 0.80 | MAOA (0.43) | MAOAPOLBRECQLMEN1KMT2A | |
| Benzoquinone SCHEMBL5335267 | 0.76 | MAOA (0.80) | MAOAPOLBRECQLMEN1KMT2A | |
| Biphenyl SCHEMBL321778 | 0.76 | ALDH1A1 (0.60) | MAOAPOLBRECQLBCHEMAPK1 | |
| SCHEMBL49870 | 0.76 | MEN1 (0.61) | MAOAPOLBRECQLMEN1KMT2A | |
| SCHEMBL11875421 | 0.76 | MEN1 (0.61) | MAOAPOLBRECQLMEN1KMT2A | |
| SCHEMBL4368339 | 0.76 | MEN1 (0.61) | MAOAPOLBRECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108401430-B | 2- (3-ethylsulfonylpyridin-2-yl) -5- (trifluoromethanesulfonyl) benzoxazole crystals | 住友化学株式会社 | 2021-06-29 | — | — | CN | disclosed |