Benzene

Benzene

SCHEMBL28580663

Clc1ccnc(Br)c1.c1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 3/20 0.38
IDO1 P14902 1/20 0.36
SOS2 Q07890 1/20 0.35
TRPA1 O75762 1/20 0.35
KMO O15229 1/20 0.35
S1PR4 O95977 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
AR P10275 1/20 0.35
MAPT P10636 3/20 0.34
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PIM1 P11309 1/20 0.34
CHKA P35790 1/20 0.34
PLA2G1B P04054 1/20 0.34
POLB P06746 1/20 0.34
XBP1 P17861 1/20 0.34
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
KMT2A Q03164 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135549 0.95
SCHEMBL29798588 0.95
Hydrochloric Acid SCHEMBL28814183 0.93
SCHEMBL9773255 0.93
Sulfuric Acid SCHEMBL28623602 0.83 ALDH1A1 (0.38) KMOKDM4CMAPTALDH1A1L3MBTL1
SCHEMBL25397821 0.71 MAP4K4 (0.46) IDO1MAPTALDH1A1KMT2A
SCHEMBL4993 0.70 NOTUM (0.48) IDO1ALDH1A1SMN1; SMN2
SCHEMBL5955760 0.70
SCHEMBL30375140 0.70 NOTUM (0.48) IDO1ALDH1A1SMN1; SMN2
SCHEMBL30240827 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109265445-B Azabiphenyl organic compound, display panel and display device 武汉天马微电子有限公司 2021-06-29 CN disclosed