SCHEMBL4993

SCHEMBL4993

Brc1cc(-c2ccccc2)ccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.48
IDO1 P14902 1/20 0.47
PLAU P00749 1/20 0.47
PIK3CA P42336 1/20 0.43
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
FDPS P14324 1/20 0.41
EGFR P00533 1/20 0.41
ASIC3 Q9UHC3 1/20 0.41
NISCH Q9Y2I1 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
NPC1 O15118 2/20 0.39
NFKB1 P19838 2/20 0.39
RAB9A P51151 2/20 0.39
NFKB2 Q00653 2/20 0.39
RELA Q04206 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ALK Q9UM73 1/20 0.39
COMT P21964 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30375140 1.00 NOTUM (0.48) NOTUMIDO1PLAUPIK3CAALDH1A1
SCHEMBL20958107 0.98 ALDH1A1 (0.46) NOTUMIDO1PLAUPIK3CAALDH1A1
SCHEMBL22912663 0.88 IDO1 (0.55) IDO1PLAUALDH1A1SMN1; SMN2BUB1
Tetrahydrofuran SCHEMBL27539541 0.86 IDO1 (0.38) NOTUMIDO1PLAUPIK3CAFDPS
SCHEMBL28460649 0.84 LMNA (0.52) NOTUMIDO1PIK3CA
SCHEMBL17445451 0.79 CYP11B1 (0.50) IDO1ALDH1A1NISCHNPC1NFKB1
SCHEMBL16341603 0.79 CYP2A6 (0.58) IDO1PIK3CAALDH1A1SMN1; SMN2
SCHEMBL25397821 0.78 MAP4K4 (0.46) IDO1PIK3CAALDH1A1
SCHEMBL28582294 0.78 IDO1 (0.44) IDO1PLAUALDH1A1SMN1; SMN2
SCHEMBL27955461 0.78 ESR1 (0.46) IDO1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029158-A EGFR inhibitors 缆图药品公司 2026-05-12 CN disclosed
US-20260059935-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-26 US disclosed
US-12528833-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-01-20 US disclosed
US-12415951-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-09-16 US disclosed
EP-3425690-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2025-06-11 EP disclosed
US-12286448-B2 Organometallic compound, organic light-emitting device including oranometallic compound, and diagnostic composition including organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-04-29 US disclosed
CN-119143812-B Phosphorescent iridium complex with inherent chiral structure, luminescent material, organic electroluminescent device and electronic equipment 季华实验室 2025-04-01 CN disclosed
EP-3439063-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2025-03-26 EP disclosed
CN-115322229-B Organic electrophosphorescent luminescent material and application thereof 北京云基科技股份有限公司 2025-02-18 CN disclosed
CN-119143812-A Phosphorescent iridium complex with inherent chiral structure, luminescent material, organic electroluminescent device and electronic equipment 季华实验室 2024-12-17 CN disclosed
US-20030085646-A1 Metal coordination compound, luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2003-05-08 US disclosed
US-20030068536-A1 Such as bis(4-biphenyl-4-yl)pyridine-C3-N3)(acetylacetonato-) iridium (III); brightness; phosphorescence; graphic arts CANON KABUSHIKI KAISHA (JP) 2003-04-10 US disclosed
US-20030065208-A1 Using palladium, nickel phosphine complex as catalysts MITSUBISHI RAYON CO., LTD. (JP) 2003-04-03 US disclosed
EP-1270582-A1 TRIPHENYLPHOSPHINE DERIVATIVE, PRODUCTION PROCESS THEREFOR, PALLADIUM COMPLEX THEREOF, AND PROCESS FOR PRODUCING BIARYL DERIVATIVE Mitsubishi Rayon Co., Ltd. (JP) 2003-01-02 EP disclosed
EP-1244155-A2 Metal coordination compound, luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2002-09-25 EP disclosed
EP-1239526-A2 Metal coordination compound, luminescene device and display apparatus CANON KABUSHIKI KAISHA (JP) 2002-09-11 EP disclosed
US-4410530-A CARDIO-SELECTIVE B-RECEPTOR BLOCKING AGENTS AND STIMULANTS CIBA-GEIGY CORPORATION (US) 1983-10-18 US disclosed
US-4291165-A DIAZOTIZATION-BROMINATION OF 2-AMINOPYRIDINE WITH HYDROGEN BROMIDE IN THE PRESENCE OF BROMINE AND SULFURIC ACID OLIN CORPORATION (US) 1981-09-22 US disclosed
US-4195090-A ADRENERGIC BLOCKING AGENTS CIBA-GEIGY CORPORATION (US) 1980-03-25 US disclosed
US-4115575-A CARDIOVASCULAR DISORDERS CIBA-GEIGY CORPORATION (US) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260059935-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, OCIAD2, OCIAD1 NOTUM 1861/4885IDO1 1463/4885PLAU 1630/4885
US-20030065208-A1 Using palladium, nickel phosphine complex as catalysts PDCD1LG2, PIK3CA, PDCD1 NOTUM 226/4885IDO1 1439/4885PLAU 4291/4885
US-20030085646-A1 Metal coordination compound, luminescence device and display apparatus CYC1, CCNL2, LEF1 NOTUM 4025/4885IDO1 348/4885PLAU 3768/4885
US-12286448-B2 Organometallic compound, organic light-emitting device including oranometallic compound, and diagnostic composition including organometallic compound ORC3, ORMDL3, OCIAD1 NOTUM 798/4885IDO1 415/4885PLAU 4558/4885
US-12415951-B2 Organic light-emitting device EML4, ICMT, L1CAM NOTUM 1161/4885IDO1 361/4885PLAU 3787/4885
US-20030068536-A1 Such as bis(4-biphenyl-4-yl)pyridine-C3-N3)(acetylacetonato-) iridium (III); brightness; phosphorescence; graphic arts CYC1, CYCS, CCNA1 NOTUM 4089/4885IDO1 47/4885PLAU 4670/4885
US-12528833-B2 Organic electroluminescent materials and devices LBR, CHRM1, OPRD1 NOTUM 4638/4885IDO1 1559/4885PLAU 4272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.