Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22371 | 0.95 | — | — | |
| SCHEMBL28240317 | 0.92 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1GAA | |
| SCHEMBL1321713 | 0.92 | — | — | |
| SCHEMBL28117813 | 0.92 | — | — | |
| Water SCHEMBL29832019 | 0.92 | — | — | |
| SCHEMBL28442031 | 0.92 | — | — | |
| Acetic Acid SCHEMBL11247935 | 0.90 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10TDP1GAA | |
| Water SCHEMBL27666659 | 0.90 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10TDP1GAA | |
| Butane SCHEMBL16795971 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10TDP1GAA | |
| Glycine SCHEMBL29244709 | 0.87 | GLRA1 (0.50) | ALDH1A1TSHRHSD17B10TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109512683-B | Povidone-iodine composition and preparation method and application thereof | 上海融澈水性材料有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-109512683-B | Povidone-iodine composition and preparation method and application thereof | 上海融澈水性材料有限公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-109512683-B | Povidone-iodine composition and preparation method and application thereof | 上海融澈水性材料有限公司 | 2021-06-15 | — | — | CN | disclosed |