Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11247935 | 0.92 | ALDH1A1 (0.45) | GLRA1SLC6A9OR51E2ALDH1A1TSHR | |
| SCHEMBL22371 | 0.92 | — | — | |
| SCHEMBL28117813 | 0.90 | — | — | |
| Water SCHEMBL29832019 | 0.90 | — | — | |
| SCHEMBL1321713 | 0.90 | — | — | |
| SCHEMBL28240317 | 0.90 | ALDH1A1 (0.47) | GLRA1SLC6A9OR51E2ALDH1A1TSHR | |
| SCHEMBL28442031 | 0.90 | — | — | |
| Water SCHEMBL27666659 | 0.87 | ALDH1A1 (0.45) | GLRA1SLC6A9OR51E2ALDH1A1TSHR | |
| Ethylenediamine SCHEMBL28580671 | 0.87 | ALDH1A1 (0.45) | GLRA1SLC6A9OR51E2ALDH1A1TSHR | |
| Butane SCHEMBL16795971 | 0.85 | ALDH1A1 (0.43) | GLRA1SLC6A9OR51E2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118320191-A | Drug coated balloon catheter for non-vascular stenosis | 优敦力公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118236560-A | Drug coated balloon catheter for non-vascular stenosis | 优敦力公司 | 2024-06-25 | — | — | CN | disclosed |