O-Xylene

O-Xylene

SCHEMBL2858075

Cc1ccccc1C.ClC(Cl)Cl

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
ACHE P22303 3/20 0.71
ALDH1A1 P00352 4/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
ESR1 P03372 1/20 0.43
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2A6 P11509 2/20 0.42
LMNA P02545 1/20 0.39
ALOX12 P18054 1/20 0.39
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
TAAR1 Q96RJ0 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HSP90AA1 P07900 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL2589554 0.90 TSHR (0.67) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL10353038 0.90 TSHR (0.67) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL6933035 0.85 TSHR (0.83) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL11035539 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL10522915 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL2854068 0.84
O-Xylene SCHEMBL170581 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL8216257 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL11034038 0.84 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL772 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100582774-C Detection method of treating prostatitis formulation GUIYANG YUNYAN XICHUANG PHARMACEUTICAL DEV CO LTD 2010-01-20 CN claimed
CN-101156893-A Mass control method of apricot red injection GUIYANG YUNYAN XICHUANG PHARM (CN) 2008-04-09 CN claimed
US-7321503-B2 Method of driving memory device to implement multiple states SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-22 US claimed
CN-1876022-A Pharmaceutical composition with red sage root and Erigeron breviscapus for treating cerebrovascular disease, its preparation process and quality control method GUIYANG YUNYAN XICHUANG PHARM (CN) 2006-12-13 CN claimed
CN-1876050-A Pharmaceutical preparation for treating prostatitis, its preparation process and quality control method GUIYANG YUNYAN XICHUANG PHARM (CN) 2006-12-13 CN claimed
CN-1876139-A Medicinal preparation for treating children's fastidium, its preparation process and quality control method GUIYANG YUNYAN XICHUANG PHARM (CN) 2006-12-13 CN claimed
CN-1853674-A Quality Control Method of Xingdan Injection YUNYANXICHUANG DRUG SCIENCE AN (CN) 2006-11-01 CN claimed
CN-1853673-A Quality controlling method of double-Danshen injection YUNYANCHUANG DRUG SCIENCE AND (CN) 2006-11-01 CN claimed
US-20060160307-A1 Method of driving memory device to implement multiple states SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-07-20 US claimed
CN-118006506-A Lactobacillus reuteri as canine source, microbial inoculum and application thereof 青岛农业大学 2024-05-10 CN disclosed
CN-116981323-A Method for preparing OPV active layer by taking sulfur-containing compound as solvent and application 中国科学院苏州纳米技术与纳米仿生研究所 2023-10-31 CN disclosed
US-9580558-B2 Polymers containing siloxane monomers ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2017-02-28 US disclosed
US-9555166-B2 Medical device with coating that promotes endothelial cell adherence ORBUSNEICH MEDICAL INC. (US) 2017-01-31 US disclosed
US-20150352263-A1 MEDICAL DEVICE WITH COATING THAT PROMOTES ENDOTHELIAL CELL ADHERENCE ORBUSNEICH MEDICAL PTE. LTD. (SG) 2015-12-10 US disclosed
US-4201869-A Intermediates for steroid total synthesis process utilizing asymmetric induction HOFFMANN-LA ROCHE INC. (US) 1980-05-06 US disclosed
US-4102925-A 1-HYDROCARBYLAMINO-3-KETO-6-(3-ALKOXY-PHENYL)-HEXAN-6-OL, INTERMEDIATES HOFFMANN-LA ROCHE INC. (US) 1978-07-25 US disclosed
US-4092483-A Intermediates for steroid total synthesis process utilizing asymmetric induction HOFFMANN-LA ROCHE INC. (US) 1978-05-30 US disclosed
US-4011211-A RING CLOSURE, ACIDS HOFFMANN-LA ROCHE INC. (US) 1977-03-08 US disclosed
US-4003949-A 3-KETO-6-(3-ALKOXYPHENYL)-1-HEXENE-6-OL HOFFMANN-LA ROCHE INC. (US) 1977-01-18 US disclosed
US-3932519-A 7,7A-Dihydro-4-[2-(3-alkoxyphenyl)-2-hydroxyethyl]-7a-alkyl-1, 5(6H)-indandiones,3,4,8,8a-tetrahydro-5-[2-(3-alkoxyphenyl)-2-hydroxyethyl]-8a-alkyl-1,6(7H)-naphthalenediones and processes for the preparation thereof utilizing asymmetric induction HOFFMANN-LA ROCHE INC. (US) 1976-01-13 US disclosed