Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | ACHE | P22303 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL2858075 | 0.90 | TSHR (0.71) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL10353038 | 0.87 | TSHR (0.67) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL6933035 | 0.82 | TSHR (0.83) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL2854068 | 0.82 | — | — | |
| O-Xylene SCHEMBL8216257 | 0.82 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL11035539 | 0.82 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL772 | 0.82 | — | — | |
| O-Xylene SCHEMBL10522915 | 0.82 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL11034038 | 0.82 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 | |
| O-Xylene SCHEMBL170581 | 0.82 | TSHR (1.00) | TSHRACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689626-B | Method for synthesizing near-infrared closed-chain sulfo-cyanine dye | 直观外科手术操作公司 | 2022-11-08 | — | — | CN | disclosed |
| US-10759729-B2 | Compounds for treating diabetes | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2020-09-01 | — | — | US | disclosed |
| EP-3481802-A1 | METHOD OF SYNTHESIZING NEAR IR, CLOSED CHAIN SULFO-CYANINE DYES | Intuitive Surgical Operations Inc. (US) | 2019-05-15 | — | — | EP | disclosed |
| CN-109689626-A | Synthesize near-infrared, closed chain sulfo group-cyanine dye method | 直观外科手术操作公司 | 2019-04-26 | — | — | CN | disclosed |
| US-20180319987-A1 | Method of Synthesizing Near IR, Closed Chain Sulfo-Cyanine Dyes | Intuitive Surgical Operations, Inc. | 2018-11-08 | — | — | US | disclosed |
| US-10053580-B2 | Method of synthesizing near IR, closed chain sulfo-cyanine dyes | Intuitive Surgical Operations, Inc. (US) | 2018-08-21 | — | — | US | disclosed |
| CN-108059589-A | Novel compounds for the treatment of diabetes | 香港中文大学 | 2018-05-22 | — | — | CN | disclosed |
| US-20180127343-A1 | NOVEL COMPOUNDS FOR TREATING DIABETES | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2018-05-10 | — | — | US | disclosed |
| US-20180009987-A1 | Method of Synthesizing Near IR, Closed Chain Sulfo-Cyanine Dyes | Intuitive Surgical Operations, Inc. (US) | 2018-01-11 | — | — | US | disclosed |
| WO-2018009375-A1 | METHOD OF SYNTHESIZING NEAR IR, CLOSED CHAIN SULFO-CYANINE DYES | Intuitive Surgical Operations, Inc. (US) | 2018-01-11 | — | — | WO | disclosed |
| US-9796854-B1 | Method of synthesizing near IR, closed chain sulfo-cyanine dyes | Intuitive Surgical Operations, Inc. (US) | 2017-10-24 | — | — | US | disclosed |
| US-8722897-B2 | Metal complexes of thiourea and derivatives as metal delivering anti-cancer and anti-inflammatory agents | GOLDPORP PHARMA LIMITED (CN) | 2014-05-13 | — | — | US | disclosed |
| US-20110269730-A1 | Metal Complexes of Thiourea and Derivatives as Metal Delivering Anti-Cancer and Anti-Inflammatory Agents | GOLDPORP PHARMA LIMITED (CN) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759729-B2 | Compounds for treating diabetes | SLC5A2, GPR119, DPP4 | TSHR 2084/4885ACHE 1563/4885ALDH1A1 481/4885 |
| US-20180009987-A1 | Method of Synthesizing Near IR, Closed Chain Sulfo-Cyanine Dyes | SPR, IK, TST | TSHR 1637/4885ACHE 2460/4885ALDH1A1 4291/4885 |
| US-10053580-B2 | Method of synthesizing near IR, closed chain sulfo-cyanine dyes | SPR, IK, TST | TSHR 1637/4885ACHE 2460/4885ALDH1A1 4291/4885 |
| US-20110269730-A1 | Metal Complexes of Thiourea and Derivatives as Metal Delivering Anti-Cancer and Anti-Inflammatory Agents | CLIC1, SLC30A5, TIA1 | TSHR 67/4885ACHE 2075/4885ALDH1A1 1053/4885 |
| US-20180319987-A1 | Method of Synthesizing Near IR, Closed Chain Sulfo-Cyanine Dyes | SPR, IK, TST | TSHR 1637/4885ACHE 2460/4885ALDH1A1 4291/4885 |
| US-20180127343-A1 | NOVEL COMPOUNDS FOR TREATING DIABETES | GPR119, SLC5A2, DPP4 | TSHR 2250/4885ACHE 2370/4885ALDH1A1 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.