SCHEMBL28580853

SCHEMBL28580853

CN1C(=O)c2ccc(O)cc2OC1(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
HTR2C P28335 1/20 0.42
MAPT P10636 2/20 0.42
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
IDO1 P14902 2/20 0.38
MALT1 Q9UDY8 1/20 0.37
WEE1 P30291 1/20 0.37
ESR1 P03372 3/20 0.37
ESR2 Q92731 3/20 0.37
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTT P42858 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1775887 0.81 CNR2 (0.47) CNR1CNR2MAOBMALT1CA1
SCHEMBL14431713 0.76 CNR1 (0.48) KDM4EALDH1A1CNR1CNR2MAPT
SCHEMBL30608424 0.71 ALDH1A1 (0.57) KDM4EALDH1A1HTR2CMAPTMAOA
SCHEMBL1314145 0.71 ALDH1A1 (0.57) KDM4EALDH1A1HTR2CMAPTMAOA
SCHEMBL1951671 0.71 ESR1 (0.40) KDM4EALDH1A1MAOAMAOBWEE1
SCHEMBL1983108 0.69 ALDH1A1 (1.00) KDM4EALDH1A1HTR2CMAPTMAOA
SCHEMBL30132496 0.69 ALDH1A1 (1.00) KDM4EALDH1A1HTR2CMAPTMAOA
SCHEMBL10713440 0.69 ALDH1A1 (0.54) KDM4EALDH1A1HTR2CMAPTMAOA
SCHEMBL17049752 0.67 KDM4E (0.51) KDM4EALDH1A1HTR2CMAPTMAOA
SCHEMBL30629205 0.66 KDM4E (0.50) KDM4EALDH1A1CNR1CNR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112876419-A Allylamine derivatives, process for producing the same and use thereof 四川科伦博泰生物医药股份有限公司 2021-06-01 CN disclosed